Two divrei torah on the Makkos:
1. (Malbim) By Klal Yisroel, the refuah precedes the makka, however, the reverse is true in regards to the other nations. Klal Yisroel only gets a makka as a means for a reawakening to do teshuva or to better their avodas Hashem, therefore the refuah precedes the makka. However, by the other nations, the makka is brought for the sake of the makka (i.e. they deserve to be punished), therefore there is no refuah prior to the makka.
This is in the passuk ??-????? ???-???? ??????, ??-???? ????, ?? ??? ???-?, ????. Meaning, I will not give over punishment to you in the same manner that I punished the Egyptians (i.e. they received punishment for the sake of punishment, you will only be punished in order to get you back on the correct path ?? ??? ???-?, ????).
#2: (Sfas Emes) There are numerous opinions as to how many makkos the Egyptians suffered. R’ Yossi HaGallili says 60, 240 is the opinion of R’ Eliezer, and Rebbi Akiva says it was 300. When you add up all those numbers you get 600. Add the 10 makkos and 3 for ??”? ??”? ???”? and you get a sum total of 613.
The lesson from this is as follows. There are 613 ways of keeping the Torah as explained in multiple places in the Zohar. Therefore, it would be inferred that there must be 613 opposite evil powers, therefore to overpower these 613 negative forces, there needed to be 613 makkos.
The same way that we can get 613 makkos out of the original 10, we also find that all 613 mitzvos are incorporated within the 10 Dibros. And the same way that the passuk tells us by the 10 makkos “???? ??????” (and only after does it say ??? ?????), it also says by the dibros “????? ????? ??????”.
Hope you’ve enjoyed and bli neder, I hope to continue to give daily pieces about the Hagadda until Yom Tov.