R’ Yisroel Salanter did not come to shul one year for Kol Nidrei. After davening, it was discovered that he had passed a house and heard a baby crying incessantly. He knocked on the door to inquire whether everything was alright and no-one came to the door. So he entered the house and found the baby left alone while the parents went to shul.
R’ Yisroel picked up the baby and held it until the parents came home. Apparently, R Yisroel felt that in that situation, holding the baby was more “spiritually uplifting” than going to Kol Nidrei.
The most spiritually uplifting thing that we can do is what Hashem wants us to do in a given situation.