There are a wide range of shitos on the subject – if you look in the sefer tehila liyona on megillah he covers a lot of them in one place. It is somewhat dependent on how you understand the story in the gemarah there of rabba shactei lrav zeira and what the conclusion of the gemarah is. There are many reasons to get drunk on Purim al pi halacha and al pi sod. That being said follow your posek/rav as the number of opinions are too numerous to list here.
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