“To postulate that the development and survival of the fittest is entirely a consequence of chance mutations seems to me a hypothesis based on no evidence and irreconcilable with the facts. These classical evolutionary theories are a gross over-simplification of an immensely complex and intricate mass of facts, and it amazes me that they are swallowed so uncritically and so readily, by so many scientists without a murmur of protest”.
-Sir Ernest Chain, co-holder of 1945 Nobel prize for developing penicillin-