One thing I will say, because I do not want to seem arrogant, is that there are many things we do not understand about the relationship of the physical world to the spiritual world. For example, I don’t think science can readily explain free-will. Any machine can only perform what it has been programmed to do. Its future state will be some function of the current state, plus the inputs. It cannot decide on its own whether it wants to do A or B. Yet humans seemingly can decide whether they want to raise their hands or not.
Presumably ones neshama decides what it wants to do, and then it commands the physical world (neurons in the brain or whatever) to proceed with A or B. How does it communicate with the physical world? It must, although no instrument could detect it. So perhaps sheidim operate at the interface of the spiritual and physical worlds, and can exert some effect upon the physical world although they are not physically detectable.
Just a brief thought, but obviously this is very complex.