Are you going to point your finger at someone sitting in a wheelchair and say, yes, I know that it was best for you to suffer in pain your whole life and not be able to walk like a normal man?
Perhaps it’s not something you should go around saying to afflicted individuals…
But if all Hashem does is for the best, then yes, that must be the case, and you know it.
You don’t know why, of course, but you know. (If you were a rabbi, and a wheelchair-bound
man asked you, “Is this really what’s best for me?,” what would you tell him?)