Reply To: What does a Chamsa symbolize in Orthodox judiasm? ✋

Just my conjecture, but I thought it supposedly wards off an Ayin Hara because it is a way (some) people hold their hand on their face when saying Kiriat Sh’ma. That reminds one to trust in Hashem. We say Hashem is one meaning the only one that can do anything.
The blue, like Techelet, reminds us of Shamayim.