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Meno,
Ok keej, here’s a hypothetical study. Let’s see what you think:
The purpose of the study is to determine the risk factor in the general population for autism.
I take a random sample of 100,000 people.
I remove 10,000 people who are wearing red socks, because I hate red socks. (I’m justified in doing this, because we can all agree that the color of one’s socks has no effect on his risk for autism, so the autism ratio in the remaining group should be the same as in the original group.)
I’m now left with 90,000 people. I find that 900 have autism. I conclude that the risk factor for autism among the general population is 1:100.
Thoughts?
You said you’re justified in removing the 10,000 with red socks. I’m not so sure. What if coincidentally, there was a concentration of either Neuro-typical or Autistic children in that group. That would make a very big difference on the resulting ratio.
In my view at this point in time, the only justification of removing anyone is if they weren’t subject to the initial risk.