Rav Yaakov Kaminetzky, son is Rav Shmuel kaminetsky
Rav Aharon Kotler’s grandson is Rav Malkiel JKotler
Rav Chaim Pinchos Scheinberg grandchildren are Gedolim
Rav Yisroel Belsky Son in law is very well known
The Second world War changed the dynamics a bit as the whole communities were uprooted from Europe and many Gedolim did not survive the war so there had to be new leadership, but that is no longer the case