The Posek Hador Rav Shmuel halevi Wosner is the PRIME example of Yichus Atzmo.
Born in Vienna to a more modern family, there was a very interesting story.
His mother was a very talented piano player or singer (not sure which). Anyways, she was offered a very prestigious position to perform in public.
The Minchas Eluzer, on a trip to Vienna at the time, told her that if she doesnt accept the job, she will have the zechus to have a son who will eventually be a Gadol Hador!!