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Aries – Now you’re really making me work, I had to look it this up in another book -Currents 2009. The other I got from my pocketbook. It says for sinusitis and PCN allergy you use Bactrim or Doxycycline. Some people will give Macrolides for PCN allergy, but it’s probably better to use one of the other two. For refractory cases, you use a newer fluoroquinolone, eg. Levaquin.