The Rav in my shul spoke about the conflict. He said that this is just a continuation of the ages-old conflict. The Parshah was significant. Eisav and Yishmael were closely connected – Eisav was Yishmael’s son-in-law.
So how does Yaakov defeat Eisav? Eisav uses his raw power. Yaakov wins by using the power of his mouth, and using it to draw closer to Hashem. The Rav told us that over Shabbos, we should make sure to use our mouths to get closer to Hashem, whether during davening, saying extra Divrei Torah at the meals, or simply singing extra zemiros. These all bring us closer to Hashem, and will help us triumph over Yishmael and Eisav.
Personally, I said an extra d’var Torah at each meal, and sang far more songs than usual. May this help us to triumph over those who wish to destroy us!