There is a difference. Women are obligated to hear the Megillah and to rejoice and partake in the Seuda on Purim, for they were part of the neis. As far as ad d’loi yoda, however, the Rivevois Ephraim (Vol.1 Ch.161) and others rule that it is inappropriate for women to become intoxicated.
Indeed the Mishna Brura (OC 199:6, in Sha’ar HaTzion), in the laws of birkas hamazon, explains that the reason women are not obligated to make a mezuman is that a mezuman should ideally be performed on a cup of wine and it is unseemly for a woman to do this.