The Alter Rebbe explains it to mean (in light of the contradicting gemara) that it means he created people who have the potential to be tzaddikim (and thus are different from others from a very young age) and those who have a greater potential to be reshaim due to their stronger yetzer / affinity for wordly things which can easily lead them to be coarser people and even reshaim.
However the intention of creating these people is so that they will overcome their yetzer for Hashem in a way that is more meaningful than even a tzaddiks Avodas Hashem in a way because he doesn’t have these struggles so its not as big of a deal when he overcomes it.
(This corresponds to the yoshev ohel vs. Ish sodeh of esav and Yaakov and why Hashem gifted yitzchak and Rivkah with esav. I can elaborate if desired.)
Hashem likes two types of avoda symbolized by the maatamim Yitzchak requested: there’s sweet food = Avodas hatzaddikim and food that starts out bitter and ends up sweet like onions = Avodas baalei teshuva who transform darkness and bitterness into light and sweet by overcoming their yetzer hara.
This should answer op