ready now
“The study does not even give doses that were administered, very. very significant omission!”
Lol! By saying that you indicate that you didnt read the study, and likely have never read any study ever, doeses are ALWAYS given..
“The mean daily dose and duration of the various drug regimens were as follows: chloroquine alone, 765 mg (SD 308) and 6·6 days (2·4); hydroxychloroquine alone, 596 mg (126) and 4·2 days (1·9); chloroquine with a macrolide, 790 mg (320) and 6·8 days (2·5); and hydroxychloroquine with a macrolide, 597 mg (128) and 4·3 days (2·0). ”
“Of course, also no zinc was used in the study! The study is not valid.”
Unclear to me , why that would make the study not valid. If you argue that it has no bearign on the use of HCQ + zinc, I could understand, but why doesnt it tell us that HCQ alone is not beneficial for covid19, and may even be harmful?
“The use of the word “may” is an unwarranted understatement.”
as the authors acknowledge “This study has several limitations. First, this was an observational retrospective analysis that could be impacted by confounding variables. This is well demonstrated by the
analyses adjusting for the difference in timing between the patients who did not receive zinc and those who did. In addition, we only looked at patients taking hydroxychloroquine and azithromycin. We do not know whether the observed added benefit of zinc sulfate to hydroxychloroquine and azithromycin on mortality would have been seen in patients who took zinc sulfate alone or in combination with just one of
those medications. We also do not have data on the time at which the patients included in the study initiated therapy with hydroxychloroquine, azithromycin, and zinc. Those
drugs would have been started at the same time as a combination therapy, but the point
in clinical disease at which patients received those medications could have differed
between our two groups. Finally, the cohorts were identified based on medications
ordered rather than confirmed administration, which may bias findings towards favoring
equipoise between the two groups. In light of these limitations, this study should not be
used to guide clinical practice. Rather, our observations support the initiation of future
randomized clinical trials investigating zinc sulfate against COVID-19.”
Its a bit strange that the authors ackowledge limitatiosn o the study but you (who clearly havent read it or the lancet study) say “The use of the word “may” is an unwarranted understatement.”
Dr. Z hasnt shown any study and has very limited anecdotal reports that don’t even tell us anything , and you jump on board.
Again to reiterate I am not disputing the study, and I am nto saying HCQ doesnt work.