Reply To: Hydroxychloroquine

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ubiquitin
Participant

Dr Zelenko’s study was published online today
“COVID-19 Outpatients – Early Risk-Stratified Treatment with Zinc Plus Low Dose Hydroxychloroquine and Azithromycin: A Retrospective Case Series Study”

I didnt read the whole thing (yet) but at first glance it suffers from the flaw I have been saying all along. what ar they beign compared to? His control group was ” public reference data of patients in the same
community who were not treated with this therapy.” . Unfortunately as the authors note ” no other patient characteristics, clinical symptoms” We dont know much about them.

And what we know about his patients does not seem to be generalizable to the population at large.
For example of his Group A (those > age 60 regardless of symptoms) seem generally healthier than the average >60 year old. 36% of them had no medical problems at all (Even when you include unrelated conditions like the 7 with psychiatric disorders) For example none had COPD. in the general population there’s a about 10% prevalence of COPD those over 60 and even higher for those > 70. How many of his control had COPD? We don’t know
The oldest person in his study was 69. How old is the control group? We dont know

So all this study tells us is that a relatively young relatively healthy group did better than the general population. Thanks to his cocktail? We don’t know

(as an aside the treated number (n) is far less than he has been advertising (Ive heard him use 1000, 600, 400 though sometimes he was referring to all patients he saw many of whom he did not treat). the study includes 127 treated patients )