Gavra-
I hope that what he meant that Hashem didn’t design them for it , and gave them talents that men don’t have for other areas. Hashem gives up what we need for the mission we have. It’s a pretty good way to figure out your mission.
Again, Beruriah was pretty darn smart – more then her husband R’ Meir ( she seems to bested him in every argument they have. Except for their last one, which unfortunately resulted in her death and R’ Meir eternal embarrassment, so I’m not sure if he chalked it up as a victory.)