First of all what are your skills, and where are you located?
Second almost no one gets a job these days by sending a CV to an add on a web site. The typical web site will put up an add and get 200 resumes, so this is not the way to go. What you need to do is network. Go to trade shows or other events where people in that field will be and meet them, shake their hands and give them your business card. Talk to your friends and see if there are openings where they would that you might fit into and so on.
There are a few good books on this:
48 Days to the work you love
Who Moved my Cheese
Fired to Hired.
There are probably others.
Also you need to make yourself stand out from the pack. If I am looking at a stack of 100cv’s I need reason to pay attention to yours