There are a few definitions for the word “Innocence”. One is “A freedom from guilt or sin through being unacquainted with evil”. According to this definition, it is possible to have innocence even after guilt or sin as long as you are longer acquainted with them.
Another definition is “A lack of knowledge”. According to this definition, once you know something in a certain area that you were before unfamiliar with, you are no longer “innocent” in that area. However, I find it difficult to establish the second definition in a Jewish light.