Yes Hachnosos orchim is only meant for one gender families and only for one gender guests. Unless of course you have a huge house with two dining rooms in which case you can split the genders into two rooms and you have two entrances one for males and one for females.
In such a case the host family has a specific schedule where the males and females of the family take turns entering the kitchen to get the food to serve in their individual dining rooms. The host father goes into the Women’s dining room to make kiddush. After that the doors are closed so the women can sing zmiros and give d’var torah where the men can’t hear. The men of course conduct their own seudah without the ability to hear or see or be tempted by any female. Hakol B’seder.