To give you an idea about the frustration. There are 7.4 billion people. At the time the gemara was written there was an estimate 1,000,000 lions. Today, the estimate is 20,000. More and more species and habitats are being destroyed every year. Hashem did not create such worldly wonders to be destroyed, made extinct, and tortured for no reason.
If you dropped your plate of chicken after a long day or got into a bad fender bender you would probably be more upset over that than the human suffering you mentioned. So maybe we shouldn’t judge others on what and what not they can be upset over.