Tomche said: “ovktd: What’s so hard to make of it? It’s a mitzvah for them to get drunk and Rav Shmuel was merely encouraging them to do a mitzvah.”
I don’t know what to make of it, because Rav Shmuel said it’s ossur to get drunk on Purim. That being what he said, I don’t understand why he would advise some bochurim to get more drunk. Unless, of course, he knew that they were exceptionally mature, and they wouldn’t do anything bad while drunk.