Newly infected COVID-19 patients have two new treatment options that can be taken at home.
But that convenience comes with a catch: The pills have to be taken as soon as possible once symptoms appear.
The challenge is getting tested, getting a prescription and starting the pills in a short window.
U.S. regulators authorized Pfizers pill, Paxlovid, and Mercks molnupiravir last week. In high-risk patients, both were shown to reduce the chances of hospitalization or death from COVID-19, although Pfizers was much more effective.
A closer look:
WHO SHOULD TAKE THESE PILLS?
The antiviral pills arent for everyone who gets a positive test. The pills are intended for those with mild or moderate COVID-19 who are more likely to become seriously ill. That includes older people and those with other health conditions like heart disease, cancer or diabetes that make them more vulnerable. Both pills were OKd for adults while Paxlovid is authorized for children ages 12 and older.
WHO SHOULDNT TAKE THESE PILLS?
Mercks molnupiravir is not authorized for children because it might interfere with bone growth. It also isnt recommended for pregnant women because of the potential for birth defects. Pfizers pill isnt recommended for patients with severe kidney or liver problems. It also may not be the best option for some because it may interact with other prescriptions a patient is taking. The antiviral pills arent authorized for people hospitalized with COVID-19.
WHATS THE TREATMENT WINDOW?
The pills have to be started as soon as possible, within five days of the start of symptoms. Cough, headache, fever, the loss of taste or smell and muscle and body aches are among the more common signs. The Centers for Disease Control and Prevention offers a website to check your symptoms.
Dr. Cameron Wolfe, an infectious disease specialist at Duke University Hospital, advises getting a test as soon as you have symptoms of COVID-19.
If you wait until you have started to get breathless, you have already to a large extent missed the window where these drugs will be helpful, Wolfe said.
WHERE CAN I GET THE PILLS?
Youll need a prescription first from a doctor or other authorized health worker. The U.S. government is buying the pills from Merck and Pfizer and providing them for free, but supplies will be limited initially. Theyll be shipped to states where they will be available at drugstores, community health centers and other places. Treatment lasts five days.
Some pharmacists may be able to administer a quick COVID-19 test and prescribe the pills all in one visit. They already do this in many states for flu or strep throat.
WILL THE PILLS WORK FOR THE OMICRON VARIANT?
The pills are expected to be effective against omicron because they dont target the spike protein where most of the variants worrisome mutations reside. The two pills work in different ways to prevent the virus from reproducing.
ARE THERE OTHER OPTIONS FOR NEW COVID-19 PATIENTS?
Yes, but they arent as easy to use as a pill: They are given by IV or injection, typically at a hospital or clinic. Three drugs provide virus-fighting antibodies, although laboratory testing suggests the two arent effective against omicron. British drugmaker GlaxoSmithKlines antibody drug appears to work, and officials say they are working to increase the U.S. supply. The only antiviral drug approved in the U.S., remdesivir, is for people hospitalized with COVID-19.
(AP)
5 Responses
Let me understand
These proven COVID Therapeutics (with a safe track record), like:
Hydroxychloroquine with Zinc = BIG NO
Ivermectin with Zinc = BIG NO
But some expensive, newly developed (non tested), potentially bad side effects, anti viral is great????
…”may be risky with other medications….”
Certainly risky, regardless if taken with other medications.
On a ratio of risk to benefit, benefit weighs in again. For Big Pharma’s pockets.
ON TARGET, you are against the vaccines, you are against the medicines. Do you suggest taking no measures against COVID? Are you for real?!?
y2r, proven therapeutics? So why so many people have been dying from COVID, especially down South and out West? I am sure they all have heard of these wonderful therapeutics.
I’m for Merck’s pill. Stromectol that is, when combined with the cocktail of nutraceuticals that many MDs prescribe.
Obviously, vaccines, that stimulate immune system once, are safer than medicines that intervene in the disease. If you look at history of FDA approvals, there were cases of medicines that were later found to have side effects and were withdrawn. All issues with vaccines were short-term after the vaccination. I did not see a case where a vaccine was withdrawn later because of a lingering side effect. So, vaccine should be your first line of defense.
Side effects seem to be manageable, as this medicine is given for a short time period and many of the problematic medications can be stopped/substituted/reduced for that time period.