The number of first responders and others diagnosed with 9/11-linked cancers has ballooned to 48,579 — a staggering 143% increase in five years, the latest data from the World Trade Center Health Program show.

Skin, prostate and breast cancer top the list, along with melanoma, lymphoma, luekemia and cancers of the thyroid, kidney, lung and bladder — believed to have been triggered by toxins at Ground Zero and the Fresh Kills landfill on Staten Island.