Pfizer says that more interim results from its ongoing coronavirus vaccine study suggest the shots are 95% effective and that the vaccine protects older people most at risk of dying from COVID-19.
The announcement, just a week after Pfizer first revealed promising preliminary results, comes as the company is preparing within days to formally ask U.S. regulators to allow emergency use of the vaccine.
Pfizer initially had estimated its vaccine, developed with German partner BioNTech, was more than 90% effective after 94 infections had been counted. With Wednesday’s announcement, the company now has accumulated 170 infections in the study — and said only eight of them occurred in volunteers who got the actual vaccine rather than a dummy shot. One of those eight developed severe disease, the company said.
The company has not yet released detailed data on its study, and results have not been analyzed by independent experts.
Pfizer said its vaccine was more than 94% effective in adults over age 65, though it is not clear how the company determined effectiveness in older adults, with only eight infections in the vaccinated group to analyze and no breakdown provided of those people’s ages.
Earlier this week Moderna, Inc. announced that its experimental vaccine appears to be 94.5% effective after an interim analysis of its late-stage study.
Pfizer says it now has the data on the vaccine’s safety needed to seek emergency authorization from the Food and Drug Administration.
The company didn’t disclose safety details but said no serious vaccine side effects have been reported, with the most common problem being fatigue after the second vaccine dose, affecting about 4% of participants.
The study has enrolled nearly 44,000 people in the U.S. and five other countries. The trial will continue to collect safety and efficacy data on volunteers for two more years.
Pfizer and BioNTech said they expect to produce up to 50 million vaccine doses globally in 2020 and up to 1.3 billion doses in 2021.
U.S. officials have said they hope to have about 20 million vaccine doses each from Moderna and Pfizer available for distribution in late December. The first shots will be offered to vulnerable groups like medical and nursing home workers, and people with serious health conditions.
(AP)
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2 Responses
1% of 40,000 is 400. It seems that both the placebo and the vaccine are in excess of 99% effective, and the 94% effectiveness is probably the extent the vaccine is more effective than the placebo. Based on their figures, even with the vaccine the chance of getting seriously ill from Covid19 is very small, and with the vaccine it will be minuscule.
With decent public relations, this will end the panic over Covid19 The figures in the test support the argument that the numbers have been exaggerated (e.g. one should not count someone has being sick from Covid19 unless they both test positive and have symptoms more severe than is possible from a cold or allergy). However even as the placebo is 99% effective, that is enough to open businesses and schools, and force anti-Semitic politicians to back down.
Toddah rabbah to Dr. Albert Bourla, a Jewish Greek & CEO of Pfizer Corp.
Suggestion: All government agencies should be downsized and have their work contracted out.
Gerry Mullen