A fire erupted in an apartment building on Manhattan�s Upper East Side early Tuesday, injuring 22 people, two of them critically, according to the Fire Department of New York.

The fire was reported at around 2 a.m. on the 24th floor of a building on East 72nd Street.

A newborn baby was among those hurt, according to WABC.

The critically injured patients were found unresponsive in a doorway, where they appeared to have collapsed while trying to escape, WABC reported.

A door was left open in the apartment where the fire started, allowing the flames to spread into the hallway.

�We had numerous phone calls from apartments above, complaining about smoke, people trapped, all due to the fact that that door was left open,� said FDNY Assistant Chief Joseph Ferrante. �Had the door been closed, this would�ve been a one apartment, one room fire.�

Those hurt included four firefighters; their injuries were minor.

Investigators are trying to figure out what sparked a high-rise fire in Manhattan that left 22 people hurt early this morning; 18 were taken to the hospital for treatment, two are in critical condition and four refused treatment. #MorningsOn1 pic.twitter.com/4D2GXxG2IH

— Spectrum News NY1 (@NY1) January 14, 2020

(AP)